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Activation and oligomerization of BAK protein

Reactome ID: R-HSA-111452

中文名称

BAK 蛋白的激活和寡聚化

通路描述

tBID 与其线粒体伴侣 BAK 结合以释放细胞色素 c。激活的 tBID 导致 BAK 发生别构激活,这可能诱导其膜内寡聚化形成孔道,从而促进细胞色素 c 外排。
英文描述
Activation and oligomerization of BAK protein tBID binds to its mitochondrial partner BAK to release cytochrome c. Activated tBID results in an allosteric activation of BAK. This may induce its intramembranous oligomerization into a pore for cytochrome c efflux.

所含基因

2 个基因