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Release of apoptotic factors from the mitochondria

Reactome ID: R-HSA-111457

中文名称

线粒体外凋亡因子的释放

通路描述

从线粒体释放的凋亡因子通过多种机制促进凋亡。细胞色素 C 参与 Apoptosome 驱动的效应级联 caspase 激活,而 SMAC 解除 IAP 介导的 caspase 抑制。
英文描述
Release of apoptotic factors from the mitochondria Apoptotic factors released from the mitochondria promote apoptosis through several different mechanisms. Cytochrome C participates in Apoptosome driven effector caspase activation while SMAC relieves IAP mediated caspase inhibition.

所含基因

6 个基因