阿片信号
中文名称
通路描述
阿片是类似鸦片中的活性物质（吗啡、可待因等）的化学物质。阿片作用通过内源性阿片受体的受体介导，如内啡肽、脑啡肽或 dynorphins。阿片具有强大的镇痛和镇静作用，并作为止痛药广泛使用。其主要副作用是快速建立强烈的成瘾。阿片受体是 G 蛋白偶联受体（GPCR）。有四种受体的类：μ（MOR）、κ（KOR）和δ（DOR），以及痛觉受体（NOP）。
英文描述
Opioid Signalling Opioids are chemical substances similar to opiates, the active substances found in opium (morphine, codeine etc.). Opioid action is mediated by the receptors for endogenous opioids; peptides such as the enkephalins, the endorphins or the dynorphins. Opioids possess powerful analgesic and sedative effects, and are widely used as pain-killers. Their main side-effect is the rapid establishment of a strong addiction. Opioids receptors are G-protein coupled receptors (GPCR). There are four classes of receptors: mu (MOR), kappa (KOR) and delta (DOR), and the nociceptin receptor (NOP).
所含基因
3 个基因