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Activation, translocation and oligomerization of BAX

Reactome ID: R-HSA-114294

中文名称

BAX 的激活、转位和寡聚化

通路描述

由于与 Bid 结合,Bax 寡聚化并整合到外膜,触发细胞色素 c 的释放。由 Bid 触发的 Bax 线粒体膜插入可能是通向凋亡途径的关键步骤(Eskes 等人,2000)。
英文描述
Activation, translocation and oligomerization of BAX As a result of binding to Bid, Bax oligomerizes and integrates in the outer mitochondrial membrane, triggering cytochrome c release. Bax mitochondrial membrane insertion triggered by Bid may represent a key step in pathways leading to apoptosis (Eskes et al., 2000).

所含基因

2 个基因