可溶性外源性抗原的跨呈递
中文名称
通路描述
树突状细胞通过跨呈递可溶性外源性抗原，尽管效率低于颗粒状底物。旨在跨呈递的可溶性抗原通过不同的内吞机制摄取，并将其路由到稳定的早期内体，然后进入细胞质进行蛋白酶体降解和肽装载。
英文描述
Cross-presentation of soluble exogenous antigens (endosomes) Exogenous soluble antigens are cross-presented by dendritic cells, albeit with lower efficiency than for particulate substrates. Soluble antigens destined for cross-presentation are taken up by distinct endocytosis mechanisms which route them into stable early endosomes and then to the cytoplasm for proteasomal degradation and peptide loading.
所含基因
42 个基因