脂筏中的 ABC 转运子
中文名称
通路描述
ABC 转运子超家族的一个定义亚集，ABCA 转运子在单核细胞和巨噬细胞中高度表达，并受胆固醇通量调节，这可能表明其在慢性炎症疾病中的作用。ABC 转运子家族的一些 D 和 G 成员在脂质运输中也具有重要意义。
英文描述
ABC transporters in lipid homeostasis A defined subset of the ABC transporter superfamily, the ABCA transporters, are highly expressed in monocytes and macrophages and are regulated by cholesterol flux which may indicate their role in in chronic inflammatory diseases (Schmitz and Kaminski 2001, Schmitz et al. 2000). Some D and G members of the ABC transporter family are also important in lipid transport (Voloshyna & Reiss 2011, Morita & Imanaka 2012, Morita et al. 2011).
所含基因
18 个基因