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Activation of BMF and translocation to mitochondria

Reactome ID: R-HSA-139910

中文名称

BMF 激活并转位至线粒体

通路描述

在健康细胞中,BMF 通过与 DLC2 相互作用与肌动蛋白 V 马达复合体结合。紫外线照射或 anoikis 诱导 MAPK8 (JNK)磷酸化 DLC2,从而释放 BMF。
英文描述
Activation of BMF and translocation to mitochondria In healthy cells, BMF is bound to the myosin V motor complex through its interaction with DLC2. UV irradiation or anoikis induces MAPK8 (JNK) to phosphorylate Dynein Light Chain 2 (DLC2) to release BMF.

所含基因

3 个基因