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Acyl chain remodelling of PG

Reactome ID: R-HSA-1482925

中文名称

磷脂酰甘油酰基链重排

通路描述

在酰基链重排途径(兰茨循环)中,磷脂酰甘油(PG)被磷脂酶水解,随后由酰基转移酶重新酰基化。这些循环修饰甘油磷脂的脂肪酸组成,生成细胞膜内不对称分布的多样化分子。此外,这些事件还发生在内质网膜(ER)和线粒体内膜(IM)中(Ghomashchi 等,2010;Singer 等,2002;Cao 等,2008;Yang 等,2004;Nie 等,2010)。
英文描述
Acyl chain remodelling of PG In the acyl chain remodelling pathway (Lands cycle), phosphatidylglycerol (PG) is hydrolyzed by phopholipases and subsequently reacylated by acyltransferases. These cycles modify the fatty acid composition of glycerophospholipids to generate diverse molecules asymmetrically distributed in the cell membrane. The events occur additionally in the inner mitochondria membranes (IM) as well as in the endoplasmic reticulum (ER) membrane (Ghomashchi et al. 2010, Singer et al. 2002, Cao et al. 2008, Yang et al. 2004, Nie et al. 2010).

所含基因

18 个基因