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Synthesis of CL

Reactome ID: R-HSA-1483076

中文名称

CL 的合成

通路描述

CL(卡氏二聚酰磷脂)在内质网膜中合成,当磷脂酰甘油(PG)和胞苷二磷酸二酰甘油(CDP-DAG)转化为CL时。除了在内质网膜中合成外,CDP-DAG也可从内质网导入,作为CL前体池。PGP(磷脂酰甘油磷酸)催化CL生物合成的限速步骤。
英文描述
Synthesis of CL Cardiolipin(CL) is synthesized in the inner mitochondrial membrane, when phosphatidylglycerol (PG) and cytidine diphosphate-diacylglycerol (CDP-DAG) are converted into CL. In addition to be synthesized in mitochondria, CDP-DAG may also be imported from ER to serve as the cardiolipin precursor pool. PGP (phosphatidylglycerol phosphate) catalyzes rate limiting step of cardiolipin biosynthesis.

所含基因

1 个基因