PG 的合成
中文名称
通路描述
磷脂酰甘油（PG）在内质网膜（IM）中合成，磷脂酸（PA）和胞苷三磷酸（CTP）转化为胞苷二磷酸二酰甘油（CDP-DAG），后者随后与甘油-3-磷酸（G3P）转化为磷脂酰甘油磷酸（PGP）和胞苷一磷酸（CMP）。最后，PGP脱磷酸化为PG。此外，PG也可在内质网膜中合成，当磷脂酶D将磷脂酰胆碱（PC）与甘油交换以取代胆碱（Cho）并形成PG时（Piazza & Marmer 2007, Stuhne-Sekalec et al. 1986, Lykidis et al. 1997, Cao & Hatch 1994）。
英文描述
Synthesis of PG Phosphatidylglycerol (PG) is synthesised at the inner mitochondrial (IM) membrane, phosphatidic acid (PA) and cytidine triphosphate (CTP) are converted into cytidine diphosphate-diacylglycerol (CDP-DAG), which in turn is converted with glycerol-3-phosphate (G3P) into phosphatidylglycerophosphate (PGP) and cytidine monophosphate (CMP). Finally, PGP is dephosphorylated to PG. In addition, PG can be synthesised at the endoplamic reticulum (ER) membrane when phospholipase D transphosphatidylates phosphatidylcholine (PC) with glycerol to displace choline (Cho) and form PG (Piazza & Marmer 2007, Stuhne-Sekalec et al. 1986, Lykidis et al. 1997, Cao & Hatch 1994).
所含基因
8 个基因