成熟内含子转录本衍生的成熟 mRNA 的转运
中文名称
通路描述
从细胞核转运至细胞质,并在此翻译为蛋白质的成熟 mRNA 的转运,具有高度的选择性,且与正确的 RNA 加工紧密耦合。这种耦合是通过核孔复合物实现的,它只识别并转运已完成的 mRNA。
英文描述
Transport of Mature mRNA derived from an Intron-Containing Transcript Transport of mRNA from the nucleus to the cytoplasm, where it is translated into protein, is highly selective and closely coupled to correct RNA processing. This coupling is achieved by the nuclear pore complex, which recognizes and transports only completed mRNAs.
所含基因
70 个基因
AAAS
ALYREF
CASC3
CDC40
CHTOP
DDX39A
DDX39B
DHX38
EIF4A3
FYTTD1
GLE1
LUZP4
MAGOH
MAGOHB
NCBP1
NCBP2
NDC1
NUP107
NUP133
NUP153
NUP155
NUP160
NUP188
NUP205
NUP210
NUP214
NUP35
NUP37
NUP43
NUP50
NUP54
NUP62
NUP85
NUP88
NUP93
NUPL2
NXF1
NXF2
NXT1
POLDIP3
POM121
POM121C
RAE1
RANBP2
RBM8A
RNPS1
SARNP
SEC13
SRRM1
SRSF1
SRSF11
SRSF2
SRSF3
SRSF4
SRSF5
SRSF6
SRSF7
SRSF9
THOC1
THOC2
THOC3
THOC5
THOC6
THOC7
TPR
U2AF1
U2AF1L4
U2AF2
UPF3B
ZC3H11A