羧基酸的偶联
中文名称
通路描述
含有羧基的异生物质和内生物质可与辅酶 A 偶联，产生酰-CoA 硫酯，然后与甘氨酸或谷氨酰胺的氨基偶联，形成酰胺键偶联物。临床重要的底物包括苯甲酸、苯乙酸和水杨酸。
英文描述
Conjugation of carboxylic acids Xenobiotics and endogenous compounds containing carboxylate groups can be activated with coenzyme A to produce acyl-CoA thioesters and then conjugated with the amino groups of glycine or glutamine to form amide-linked conjugates. Clinically important substrates include benzoic acid, phenylacetic acid, and salicylic acid.
所含基因
4 个基因