同型半胱氨酸转化为半胱氨酸
中文名称
通路描述
转硫酸化是同型半胱氨酸和半胱氨酸之间的相互转化，它完全发生在细菌和一些植物及真菌中。然而，动物只有这种双向路径中的一个方向，即通过胱氨酸从同型半胱氨酸合成半胱氨酸。由于过量的半胱氨酸被降解为硫化氢，现已知这是一种神经调节剂和平滑肌松弛剂，因此该途径也是其主要来源，发生在细胞质中，以及细胞外空间（Dominy & Stipanuk 2004, Bearden et al. 2010）。
英文描述
Cysteine formation from homocysteine Transsulfuration is the interconversion of homocysteine and cysteine, and it fully takes place in bacteria and some plants and fungi. Animals however have only one direction of this bidirectional path, the synthesis of cysteine from homocysteine via cystathionine. Because excess cysteine is degraded to hydrogen sulfide, which is now known as a neuromodulator and smooth muscle relaxant, this pathway is also the main source of its production, which takes place in the cytosol, as well as in extracellular space (Dominy & Stipanuk 2004, Bearden et al. 2010).
所含基因
2 个基因