Tat介导的HIV延伸停滞与恢复
中文名称
通路描述
RNA Pol II停滞被认为是酶不可逆地后退约7-14个核苷酸的结果。TFIIS通过促进新生转录本约7-14个核苷酸上游的切除来激活停滞的RNA Pol II。
英文描述
Tat-mediated HIV elongation arrest and recovery RNA Pol II arrest is believed to be a result of irreversible backsliding of the enzyme by ~7-14 nucleotides. TFIIS reactivates arrested RNA Pol II by promoting the excision of nascent transcript ~7-14 nucleotides upstream of the 3' end.
所含基因
29 个基因