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HIV elongation arrest and recovery

Reactome ID: R-HSA-167287

中文名称

HIV延伸停滞与恢复

通路描述

RNA Pol II停滞被认为是酶不可逆地后退约7-14个核苷酸的结果。TFIIS通过促进新生转录本约7-14个核苷酸上游的切除来激活停滞的RNA Pol II。
英文描述
HIV elongation arrest and recovery RNA Pol II arrest is believed to be a result of irreversible backsliding of the enzyme by ~7-14 nucleotides. TFIIS reactivates arrested RNA Pol II by promoting the excision of nascent transcript ~7-14 nucleotides upstream of the 3' end.

所含基因

31 个基因