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APC/C:Cdc20 mediated degradation of Cyclin B

Reactome ID: R-HSA-174048

中文名称

APC/C:Cdc20 介导的 Cyclin B 降解

通路描述

Cyclin B1 的降解似乎发生在有丝分裂纺锤体上,直到纺锤体组装检查点延迟到有丝分裂/有丝分裂转换,这对于姐妹染色单体的分离是必需的(Geley et al. 2001; Hagting et al, 2002)。
英文描述
APC/C:Cdc20 mediated degradation of Cyclin B The degradation of cyclin B1, which appears to occur at the mitotic spindle, is delayed until the metaphase /anaphase transition by the spindle assembly checkpoint and is required in order for sister chromatids to separate (Geley et al. 2001;Hagting et al, 2002).

所含基因

24 个基因