端粒 C 链的连续合成
中文名称
通路描述
一旦 Pol alpha 切换到 Pol delta 完成，短 DNA 片段 Okazaki 片段（Okazaki fragment）的连续合成便开始了。DNA 合成是不连续的，随着延伸的 Okazaki 片段到达 RNA 引物，该引物折叠成单链凸起结构，并由内切酶切除。延伸过程由相邻 Okazaki 片段的连接完成。
英文描述
Processive synthesis on the C-strand of the telomere Once polymerase switching from pol alpha to pol delta is complete the processive synthesis of a short run of DNA called an Okazaki fragment begins. DNA synthesis is discontinuous and as the extending Okazaki fragment reaches the RNA primer, this primer is folded into a single-stranded flap, which is removed by endonucleases. The process of extension is completed by the ligation of adjacent Okazaki fragments.
所含基因
14 个基因