GAG 蛋白的膜结合和靶向
中文名称
通路描述
Gag 蛋白参与 HIV 病毒组装的一个谜团是这些蛋白质如何被靶向到正确膜上进行出芽。感染性逆转录病毒不从感染细胞内所有可用的膜表面出芽，但主要从血浆膜出芽，这在大多数细胞中仅占总膜表面积的一小部分。在极性细胞中，出芽位点进一步限制在下基侧膜。
英文描述
Membrane binding and targetting of GAG proteins One of the mysteries of Gag protein involvement in HIV virion assembly is how the proteins are targeted to the proper membrane for budding. Infectious retroviruses do not bud from all of the available membrane surfaces within an infected cell, but primarily from the plasma membrane, which constitutes a small proportion of the total membrane surface in most cells. In polarized cells, the sites of budding are further restricted to the basolateral membrane.
所含基因
14 个基因