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Phosphorylation of the APC/C

Reactome ID: R-HSA-176412

中文名称

APC/C 的磷酸化

通路描述

APC 亚基的磷酸化对于 APC/C 在中期到后期转换时由 Cdc20 介导的激活是必需的(Kramer et al., 2000)。虽然体内负责磷酸化的具体激酶尚未完全确定,但 Plk1 和 Cyclin B:Cdc2 均被认为与此过程有关。
英文描述
Phosphorylation of the APC/C Phosphorylation of APC subunits is required for Cdc20 mediated activation by of the APC/C at the metaphase anaphase transition (Kramer et al., 2000). While the kinases responsible for phosphorylation in vivo have not been determined with certainty, both Plk1 and Cyclin B:Cdc2 have been implicated in this process.

所含基因

20 个基因