苯甲酸与甘氨酸的共轭
中文名称
通路描述
苯甲酸作为食品防腐剂广泛使用，通过与甘氨酸活化共轭转化为乌头酸。这是最早发现的解毒途径之一，曾以前作为尿素循环缺陷患者氮排泄的替代临床手段被利用（Brusilow and Horwich 2001）。
英文描述
Conjugation of benzoate with glycine Benzoic acid, widely used as a food preservative, is converted to hippuric acid by activation and conjugation with glycine. This was one of the first detoxification pathways discovered, and was formerly exploited clinically as an alternative means of nitrogen excretion in patients with urea cycle defects (Brusilow and Horwich 2001).
所含基因
6 个基因