FGFR1c和Klotho配体结合与激活
中文名称
通路描述
FGF23属于FGF家族的内分泌亚家族。它产生于骨组织并调节肾脏功能。Klotho对于内源性FGF23功能至关重要,因为它将FGFR1c转化为特定的FGF23受体。
英文描述
FGFR1c and Klotho ligand binding and activation FGF23 is a member of the endocrine subfamily of FGFs. It is produced in bone tissue and regulates kidney functions. Klotho is essential for endogenous FGF23 function as it converts FGFR1c into a specific FGF23 receptor.
所含基因
2 个基因