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FGFR1c and Klotho ligand binding and activation

Reactome ID: R-HSA-190374

中文名称

FGFR1c和Klotho配体结合与激活

通路描述

FGF23属于FGF家族的内分泌亚家族。它产生于骨组织并调节肾脏功能。Klotho对于内源性FGF23功能至关重要,因为它将FGFR1c转化为特定的FGF23受体。
英文描述
FGFR1c and Klotho ligand binding and activation FGF23 is a member of the endocrine subfamily of FGFs. It is produced in bone tissue and regulates kidney functions. Klotho is essential for endogenous FGF23 function as it converts FGFR1c into a specific FGF23 receptor.

所含基因

2 个基因