轴突导向
中文名称
通路描述
轴突导向是神经元网络形成的关键阶段。轴突由多种导向因子引导，如净触蛋白、Ephrins、Slits 和半胱胺。这些导向信号被生长锥上的受体读取，下游的信号转导通路汇聚到Rho GTPases上，引发细胞骨架组织的改变，从而决定生长锥转向的方向。
英文描述
Gap junction degradation The half-life of Cx is very short (1 to 5h) compared to other junctional proteins (Laird et al., 1995 ; Fallon and Goudenough, 1981). Connexins are targeted for degradation by the proteasome and the lysosome. Degradation appears to involve the phosphorylation of Connexins as well as their interactions with other proteins (Piehl et al., 2007).
所含基因
12 个基因