p75NTR 通过 SC1 负向调节细胞周期
中文名称
通路描述
SC1（施万细胞因子 1；也称为 PR 结构域锌指蛋白 4，PRDM4）与 NGF:p75NTR 复合物相互作用，并通过调节细胞周期蛋白 E 的水平来信号化细胞周期停滞。
英文描述
p75NTR negatively regulates cell cycle via SC1 SC1 (Schwann Cell factor 1; also called PR domain zinc finger protein 4, PRDM4) interacts with an NGF:p75NTR complex and signals cell cycle arrest by regulating the levels of cyclin E.
所含基因
6 个基因