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Ceramide signalling

Reactome ID: R-HSA-193681

中文名称

鞘脂信号传导

通路描述

在某些细胞类型中,配体与p75NTR结合可诱导鞘脂产生,这既可介导细胞存活(例如在神经节细胞中),也可介导细胞凋亡(例如在少突胶质细胞中)。鞘脂水平较低时,也能刺激海马神经元轴突生长。
英文描述
Ceramide signalling In certain cell types, ligand binding to p75NTR leads to ceramide production, which can mediate either cell survival (e.g. in noecotical subplate neurons) or apoptosis (e.g. in oligodendrocytes). Low levels of ceramide are also able to stimulate axonal outgrowth in hippocampal neurons.

所含基因

3 个基因