生物素运输和代谢
中文名称
通路描述
生物素 (Btn) 是多种羧化反应的必需辅因子 (Zempleni et al. 2009)。人类无法合成生物素，但其在人类饮食中丰富，可通过 SLC5A6 转运蛋白从肠腔摄取。其摄取、细胞内转运、与无酶蛋白的共价结合以及补救代谢在此描述。
英文描述
Biotin transport and metabolism Biotin (Btn) is an essential cofactor in a variety of carboxylation reactions (Zempleni et al. 2009). Humans cannot synthesize Btn but it is abundant in the human diet and can be taken up from the intestinal lumen by the SLC5A6 transporter. Its uptake, intracellular translocation, covalent conjugation to apoenzymes, and salvage are described here.
所含基因
11 个基因