RIP介导的NF-kB激活通过ZBP1
中文名称
通路描述
人源或小鼠ZBP1（DAI）在HEK293T细胞中的过表达以剂量依赖性方式激活了NF-kB依赖的启动子。RIP1和RIP3两种RHIM结构域含的激酶参与ZBP1诱导的NF-kB激活（Rebsamen M等2009；Kaiser WJ等2008）。
英文描述
Vitamin B2 (riboflavin) metabolism Riboflavin (vitamin B2, E101) is an essential component for the cofactors FAD (flavin-adenine dinucleotide) and FMN (flavin mononucleotide). Together with NAD+ and NADP+, FAD and FMN are important hydrogen carriers and take part in more than 100 redox reactions involved in energy metabolism. Riboflavin is present in many vegetables and meat and during digestion, various flavoproteins from food are degraded and riboflavin is resorbed. The major degradation and excretion product in humans is riboflavin (Rivlin 1970).
所含基因
7 个基因