AKT 磷酸化细胞质靶标
中文名称
通路描述
激活后，AKT 可以在细胞质中磷酸化一系列靶蛋白，其中许多与细胞存活控制有关。TSC2 的磷酸化正向促进 TOR 激酶，进而促进 AKT 激活（正反馈循环）。
英文描述
AKT phosphorylates targets in the cytosol Following activation, AKT can phosphorylate an array of target proteins in the cytoplasm, many of which are involved in cell survival control. Phosphorylation of TSC2 feeds positively to the TOR kinase, which, in turn, contributes to AKT activation (positive feedback loop).
所含基因
14 个基因