糖蛋白激素
中文名称
通路描述
具有糖侧链的复杂蛋白质激素被称为糖蛋白激素。此类激素包括促卵泡激素(FSH;促卵泡刺激素)、黄体生成素(LH)、甲状腺刺激激素(TSH;促甲状腺激素)和人绒毛膜促性腺激素(hCG)。糖蛋白激素的α亚基是一个 92 个氨基酸的肽段,作为 FSH、LH、hCG 和 TSH 的α亚基(Fiddes JC 和 Goodman HM, 1981)。这些激素的β亚基具有独特性,赋予它们生物学特异性。这两个亚基通过二硫键结合形成成熟的糖蛋白激素二聚体。
英文描述
Glycoprotein hormones More complex protein hormones have carbohydrate side chains and are called glycoprotein hormones. Hormones in this class are Follicle-stimulating hormone (FSH; follitropin), Luteinizing hormone (LH), Thyroid-stimulating hormone (TSH; thyrotropin) and human chorionic gonadotropin (hCG). The alpha subunit of glycoprotein hormones is a 92 aa peptide and serves as the alpha subunit for FSH, LH, hCG and TSH (Fiddes JC and Goodman HM, 1981). The beta subunits for these hormones are unique and confer biological specificity to them. These two subunits combine via disulphide bonding to produce the mature glycoprotein hormone dimer.
所含基因
10 个基因