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Catecholamine biosynthesis

Reactome ID: R-HSA-209905

中文名称

儿茶酚胺生物合成

通路描述

儿茶酚胺类神经递质多巴胺、去甲肾上腺素和肾上腺素存在于动物的神经组织中。它们由酪氨酸通过四种酶合成:酪氨酸羟化酶(TH)、芳香族 L-氨基酸脱羧酶(AADC)、多巴胺β-羟化酶(DBH)和苯乙醇胺 N-甲基转移酶(PNMT)。
英文描述
Catecholamine biosynthesis The catecholamine neurotransmitters dopamine, noradrenaline and adrenaline are found in nervous tissue of animals. They are synthesized in catecholaminergic neurons by four enzymes from tyrosine to adrenaline: tyrosine hydroxylase (TH); aromatic L-amino acid decarboxylase (AADC); dopamine beta-hydroxylase (DBH); and phenylethanolamine N-methyltransferase (PNMT).

所含基因

4 个基因