PS-GAP/RHG10 对 PAK-2p34 活性的调节
中文名称
通路描述
PS-GAP (RGH10) 特异性地与 caspase 激活的 PAK-2p34 相互作用，减少 PAK-2p34 诱导细胞死亡的能力。该相互作用抑制 PAK-2p34 的激酶活性，并将 PAK-2p34 的定位从细胞核改变为细胞质周边区域（Koeppel et al., 2004）。
英文描述
Regulation of PAK-2p34 activity by PS-GAP/RHG10 PS-GAP (RGH10) interacts specifically with caspase-activated PAK-2p34 reducing the ability of PAK-2p34 to induce cell death. This interaction inhibits the kinase activity of PAK-2p34 and changes the localization of PAK-2p34 from the nucleus to the perinuclear region (Koeppel et al., 2004).
所含基因
2 个基因