二苯基代谢过程
中文名称
通路描述
涉及二苯基的化学反应和途径，二苯基是一种有毒的芳香烃，用作传热介质，并在包装柑橘水果和植物病害控制中用作杀菌剂。二苯基可与1-10个氯分子氯化形成多氯联苯（PCBs）。
英文描述
CYP2E1 reactions CYP2E1 can metabolize and activate a large number of solvents and industrial monomers as well as drugs. This quality of CYP2E1 may make it an important determinant of human susceptibility to the toxic effects of industrial and environmental chemicals. Typical CYP2E1 substrates include acetaminophen, benzene, CCl4, halothane, ethanol and vinyl chloride. CYP2E1 contributes to oxidative stress by producing oxidising species called reactive oxygen species (ROS) which can lead to damage to mitochondria, DNA and initiate lipid peroxidation or even cell death.
所含基因
11 个基因