视杆细胞中的经典视黄醇循环（暗视觉）
中文名称
通路描述
视黄醇循环（也称为视觉循环）是视觉色素 11-顺式视黄醛（11cRAL）从光激活的视蛋白中以全反式视黄醛的形式释放，并异构化为 11-顺式异构体以供下一次光异构化反应的过程。该过程涉及氧化、还原和异构化反应，发生在视网膜色素上皮（RPE）和眼睛的感光细胞段中（von Lintig 2012, Blomhoff & Blomhoff 2006, von Lintig 等人 2010, D'Ambrosio 等人 2011）。本节描述了暗光/黄昏条件下视杆细胞中的视黄醇循环。
英文描述
The canonical retinoid cycle in rods (twilight vision) The retinoid cycle (also referred to as the visual cycle) is the process by which the visual chromophore 11-cis-retinal (11cRAL) is released from light-activated opsins in the form all-trans-retinal and isomerized back to its 11-cis isomer ready for another photoisomerization reaction. This process involves oxidation, reduction and isomerization reactions and take place in the retinal pigment epithelium (RPE) and photoreceptor segments of the eye (von Lintig 2012, Blomhoff & Blomhoff 2006, von Lintig et al. 2010, D'Ambrosio et al. 2011). This section describes the retinoid cycle in rods during dark/twilight conditions.
所含基因
22 个基因