CDH11同源和异源相互作用
中文名称
通路描述
基于表面等离子体共振实验，CDH11与CDH8形成特异性亚群，可能还与CDH24相互作用。CDH11形成同源二聚体（Patel et al. 2006, Brasch et al. 2018），并与CDH8形成异源二聚体（Brasch et al. 2018），基于序列相似性，可能也与CDH24相互作用（Brasch et al. 2018）。
英文描述
Apoptotic cleavage of cell adhesion proteins Apoptotic cells show dramatic rearrangements of tight junctions, adherens junctions, and desmosomes (Abreu et al., 2000). Desmosome-specific members of the cadherin superfamily of cell adhesion molecules including desmoglein-3, plakophilin-1 and desmoplakin are cleaved by caspases after onset of apoptosis (Weiske et al., 2001). Cleavage results in the disruption of the desmosome structure and thus contributes to cell rounding and disintegration of the intermediate filament system (Weiske et al., 2001).
所含基因
11 个基因