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Class A/1 (Rhodopsin-like receptors)

Reactome ID: R-HSA-373076

中文名称

类 A/1(视紫红质样受体)

通路描述

类 A/1(视紫红质样受体)是 GPCRs 中最大的群体,也是从功能和结构角度研究最深入的群体。它们在序列水平上表现出巨大的多样性,因此可以根据系统发育分析(Joost P 和 Methner A, 2002)将其分为 19 个亚家族(亚家族 A1-19)。它们包括激素、光和神经递质受体,涵盖广泛的函数,包括许多自分泌、旁分泌和内分泌过程。
英文描述
Class A/1 (Rhodopsin-like receptors) Rhodopsin-like receptors (class A/1) are the largest group of GPCRs and are the best studied group from a functional and structural point of view. They show great diversity at the sequence level and thus, can be subdivided into 19 subfamilies (Subfamily A1-19) based on a phylogenetic analysis (Joost P and Methner A, 2002). They represent members which include hormone, light and neurotransmitter receptors and encompass a wide range of functions including many autocrine, paracrine and endocrine processes.

所含基因

19 个基因