返回搜索

Eicosanoid ligand-binding receptors

Reactome ID: R-HSA-391903

中文名称

二十烷酸受体

通路描述

二十烷酸来源于多不饱和 20 碳脂肪酸,是炎症、平滑肌收缩和血液凝固的旁分泌和自分泌调节剂。二十烷酸的作用通过二十烷酸受体介导,其中大多数是 GPCRs。人类中有四种类型的二十烷酸 GPCRs:白三烯、脂氧素(Brink C et al, 2003)、前列腺素(Coleman RA et al, 1994)和氧二十烷酸(Brink C et al, 2004)受体。
英文描述
Eicosanoid ligand-binding receptors Eicosanoids, derived from polyunsaturated 20-carbon fatty acids, are paracrine and autocrine regulators of inflammation, smooth muscle contraction, and blood coagulation. The actions of eicosanoids are mediated by eicosanoid receptors, most of which are GPCRs. There are four types of eicosanoid GPCRs in humans; leukotriene, lipoxin (Brink C et al, 2003), prostanoid (Coleman RA et al, 1994) and oxoeicosanoid (Brink C et al, 2004) receptors.

所含基因

1 个基因