P2Y 受体
中文名称
通路描述
P2Y 受体是一类嘌呤能受体，由 ATP、ADP、UTP、UDP 和 UDP-葡萄糖等核苷酸刺激。迄今为止，已在人类中克隆出 12 种 P2Y 受体（Abbracchio MP 等，2006；Fischer W 和 Krugel U，2007）。P2Y 受体几乎存在于所有人类组织中，并根据其 G 蛋白偶联特性发挥各种生物学功能。嘌呤核苷酸参与大量中间代谢途径，作为底物、产物或变构因子发挥作用。
英文描述
P2Y receptors P2Y receptors are a family of purinergic receptors, G protein-coupled receptors stimulated by nucleotides such as ATP, ADP, UTP, UDP and UDP-glucose. To date, 12 P2Y receptors have been cloned in humans (Abbracchio MP et al, 2006; Fischer W and Krugel U, 2007). P2Y receptors are present in almost all human tissues where they exert various biological functions based on their G-protein coupling. Purine nucleotides are involved in a large number of intermediate metabolic pathways, taking part as substrates, products or allosteric factors.
所含基因
12 个基因