类 C/3（代谢性谷氨酸/趋化因子受体）
中文名称
通路描述
类 C G 蛋白偶联受体是一类 G 蛋白偶联受体，包括代谢性谷氨酸受体和几种附加受体（Brauner-Osborne H 等，2007）。类 C GPCRs 具有大的胞外 N 端，该 N 端结合内源性配体（配体）。该结构域的形状常被比作蛤蜊。已鉴定出几种作用于这些受体的配体，这些配体结合在七跨膜区域。
英文描述
Class C/3 (Metabotropic glutamate/pheromone receptors) The class C G-protein-coupled receptors are a class of G-protein coupled receptors that include the metabotropic glutamate receptors and several additional receptors (Brauner-Osborne H et al, 2007). Family C GPCRs have a large extracellular N-terminus which binds the orthosteric (endogenous) ligand. The shape of this domain is often likened to a clam. Several allosteric ligands to these receptors have been identified and these bind within the seven transmembrane region.
所含基因
40 个基因