Nectin/Necl 跨膜异二聚化
中文名称
通路描述
Nectins 和 Nectin 样分子（Necls）也经历跨异二聚相互作用，与其他 Nectin 或 Necl 家族成员相互作用。除了 Nectins 和 Nectin 样分子之间的跨相互作用外，还描述了 Nectins 或 Necls 与其他免疫球蛋白超家族成员（如 CD96、CD226 和 CRTAM）之间的跨同源相互作用（Sakisaka 等，2007；Takai 等，2008）。应注意的是，其中一些相互作用可能不存在于上皮细胞 - 细胞接触中，但可能发生在其他细胞 - 细胞粘附系统中。
英文描述
Nectin/Necl trans heterodimerization Nectins and Nectin-like molecules (Necls) also undergo trans-heterophilic interactions to interact with other nectin or Necl family members. Besides these trans interactions among nectins and nectin-like family members, trans-homophilic interactions have also been described between nectins or Necls with other immunoglobulin-superfamily members like CD96, CD226 and CRTAM (Sakisaka et al., 2007; Takai et al., 2008). It should be noted that some of these interactions might not exist in epithelial cell-cell contacts but may occur in other cell-cell adhesion systems.
所含基因
7 个基因