肌醇转运子
中文名称
通路描述
肌醇是中性环状多醇，在哺乳动物组织中丰富。它发挥重要作用；它是磷脂酰肌醇（PtdIns）和肌醇磷酸（IP）的前体，后者作为第二信使和许多细胞功能的调节者。它还可以作为相容性渗透调节剂，在暴露于高渗条件的许多组织中调节体积。葡萄糖转运子家族的三个成员是肌醇转运子。两个（SMIT1和SMIT2）与两个Na+离子耦合肌醇转运。与SMIT1不同，SMIT2还转运D-赤藓糖醇。第三个转运子（HMIT）与质子耦合肌醇转运。
英文描述
Inositol transporters Myo-Inositol is a neutral cyclic polyol, abundant in mammalian tissues. It plays important roles; it is a precursor to phosphatidylinositols (PtdIns) and to the inositol phosphates (IP), which serve as second messengers and as key regulators of many cell functions. It can also serve as a compatible osmolyte during volume regulation in many tissues where cells are exposed to hyperosmotic conditions. Three members of the glucose transporter families are inositol transporters. Two (SMIT1 and SMIT2) couple myo-inositol transport with two Na+ ions. Unlike SMIT1, SMIT2 also transports D-chiro_inositol. The third transporter (HMIT), couples myo-inositol transport with a proton.
所含基因
3 个基因