针对杂合N-糖基化通路的反应
中文名称
通路描述
MGAT3介导的半介导GlcNAc转移将通路导向杂合糖链的合成，因为MAN2无法作用于半介导寡糖。在组织中MGAT3过表达MGAT2可调节杂合糖链向复杂N-糖链的合成。GlcNAc的添加也阻止了MGAT4、MGAT5和FUT8的作用。
英文描述
Synthesis of UDP-N-acetyl-glucosamine UDP-acetylglucosamine acts as a donor for the first two steps of the N-glycan precursor biosynthesis pathway, and is later used as a substrate for further modifications after the precursor has been attached to the protein. It is synthesized from fructose 6-phosphate, glutamine, acetyl-CoA, and UTP in four steps.
所含基因
8 个基因