初始补体激活
中文名称
通路描述
补体激活是由某些成分中的丝氨酸蛋白酶域执行的蛋白酶解级联反应。根据靶标结合的抗体（经典途径）、微生物多糖结构（凝集素途径）或其他'外来'表面结构的识别（替代途径）由 C3b 触发，这三种途径都汇聚到 C3 和 C5 的关键激活，随后由高度特异性的酶复合物（称为 C3/C5 转化酶）激活。仅存在于有颌脊椎动物的补体系统包含三种 C3 激活途径和共同的裂解途径。
英文描述
Fructose biosynthesis The conversion of glucose to fructose via sorbitol was demonstrated by Hers (1960) in the seminal vesicles of sheep, has since been demonstrated as well in human epidydimal tissue (Frenette et al. 2006), and appears to be the physiological source of the abundant fructose found in seminal fluid. The enzymes of the pathway are likewise abundant in the eye lens and in neurons, where their physiological role is less clear but where they appear to play a central role in diabetic tissue damage (Oates 2008).
所含基因
2 个基因