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Highly sodium permeable postsynaptic acetylcholine nicotinic receptors

Reactome ID: R-HSA-629587

中文名称

高度钠通透的突触后乙酰胆碱烟碱型受体

通路描述

具有低 Ca2+ 通透性的烟碱型乙酰胆碱受体允许 Na+ 流入,导致膜去极化,引发电压依赖性反应,如电压依赖性 Ca2+ 通道的开放,从而增加 Ca2+ 并启动下游信号。这些受体可在突触前和突触后终末中找到。
英文描述
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors Nicotinic acetylcholne receptors that have low Ca2+ permeability allow the influx of Na+ which causes depolarization of the membrane initiating voltage dependent responses such as activation of voltage dependent opening of Ca2+ channels and thus eliciting an increase in Ca2+ and downstream signaling. These receptors could be found in both presynaptic and postsynaptic terminals.

所含基因

7 个基因