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TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain

Reactome ID: R-HSA-6803205

中文名称

TP53 调节转录的几种其他细胞死亡基因,其在 p53 依赖性凋亡中的具体作用尚不确定

通路描述

其他促凋亡 TP53(p53)靶基因(如 TP53I3、RABGGTA、BCL2L14、BCL6、NDRG1 和 PERP)的作用机制尚不确定(参见 Attardi 等,2000;Guo 等,2001;Samuels-Lev 等,2001;Contente 等,2002;Ihrie 等,2003;Bergamaschi 等,2004;Stein 等,2004;Phan 和 Dalla-Favera 等,2004;Jen 和 Cheung 等,2005;Margalit 等,2006;Zhang 等,2007;Saito 等,2009;Davies 等,2009;Giam 等,2012)。
英文描述
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain The exact mechanisms of action of several other pro-apoptotic TP53 (p53) targets, such as TP53I3 (PIG3), RABGGTA, BCL2L14, BCL6, NDRG1 and PERP, remain uncertain (Attardi et al. 2000, Guo et al. 2001, Samuels-Lev et al. 2001, Contente et al. 2002, Ihrie et al. 2003, Bergamaschi et al. 2004, Stein et al. 2004, Phan and Dalla-Favera 2004, Jen and Cheung 2005, Margalit et al. 2006, Zhang et al. 2007, Saito et al. 2009, Davies et al. 2009, Giam et al. 2012).

所含基因

14 个基因