DNA复制起始
中文名称
通路描述
DNA聚合酶不能从头合成DNA，需要合成引物，通常由DNA依赖的RNA聚合酶（引物酶）合成。在真核细胞中，引物由DNA聚合酶alpha:引物酶合成。首先，DNA引物酶部分合成约6-10个核苷酸的RNA引物，然后DNA聚合酶部分合成额外的20个核苷酸的DNA（Frick & Richardson 2002; Wang et al 1984）。
英文描述
DNA replication initiation DNA polymerases are not capable of de novo DNA synthesis and require synthesis of a primer, usually by a DNA-dependent RNA polymerase (primase) to begin DNA synthesis. In eukaryotic cells, the primer is synthesized by DNA polymerase alpha:primase. First, the DNA primase portion of this complex synthesizes approximately 6-10 nucleotides of RNA primer and then the DNA polymerase portion synthesizes an additional 20 nucleotides of DNA (Frick & Richardson 2002; Wang et al 1984).
所含基因
8 个基因