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Histidine catabolism

Reactome ID: R-HSA-70921

中文名称

组氨酸分解代谢

通路描述

组氨酸分解代谢的主要途径(此处标注)包含四个步骤,生成谷氨酸,同时在一分子四氢叶酸转化为 5-氨基四氢叶酸的过程中进行(Morris 等,1972)。组氨酸也可脱羧生成组胺。组氨酸也可用于形成组氨酸β-丙氨酸(β-丙氨酸-L-组氨酸),这是一种在大多数脊椎动物的骨骼肌和大脑中丰富的二肽。
英文描述
Histidine catabolism The major pathway of histidine catabolism, annotated here, proceeds in four steps to yield glutamate and, in the process, convert one molecule of tetrahydrofolate to 5-formiminotetrahydrofolate (Morris et al. 1972). Histidine can also be decarboxylated to form histamine. Histidine can also be used to form carnosine (beta-alanyl-L-histidine), an abundant dipeptide in skeletal muscle and brain of most vertebrates.

所含基因

9 个基因