肌酸代谢
中文名称
通路描述
在人类中，肌酸主要在肝脏和肾脏中合成，从甘氨酸、精氨酸和 S-腺苷甲硫氨酸开始，经过两步反应。从肝脏，肌酸被转运到骨骼肌和脑等组织，在那里发生磷酸化，作为短期能量储备。肌酸离开产生组织的机制尚不清楚，但消费者组织的摄取由 SLC6A8 转运蛋白介导。一旦形成，磷酸肌酸会缓慢自发反应生成肌酸酐，并从体内排出。
英文描述
Creatine metabolism In humans, creatine is synthesized primarily in the liver and kidney, from glycine, arginine, and S-adenosylmethionine, in a sequence of two reactions. From the liver, creatine is exported to tissues such as skeletal muscle and brain, where it undergoes phosphorylation and serves as a short-term energy store. The mechanism by which creatine leaves producer tissues is unclear, but its uptake by consumer tissues is mediated by the SLC6A8 transporter.Once formed, phosphocreatine undergoes a slow spontaneous reaction to form creatinine, which is excreted from the body.
所含基因
10 个基因