核糖体扫描和起始密码子的识别

中文名称

核糖体扫描和起始密码子的识别

通路描述

80S核糖体结合mRNA沿mRNA分子从其起始位点移动到起始密码子并形成48S复合物，其中起始密码子与Met-tRNAi的反密码子碱基配对。起始密码子AUG的正确识别依赖于与Met-tRNAi反密码子的碱基配对，并需要eIF1、eIF1A、eIF2和eIF5。

英文描述

Ribosomal scanning and start codon recognition The 80S ribosome bound to the mRNA moves along the mRNA molecule from its initial site to the initiation codon and forms a 48S complex, in which the initiation codon is base paired to the anticodon of the Met-tRNAi. Proper recognition of the AUG initiation codon depends on base pairing with the anticodon of the Met-tRNAi and requires eIF1, eIF1A, eIF2 and eIF5.

所含基因

59 个基因

EIF1AX EIF2S1 EIF2S2 EIF2S3 EIF3A EIF3B EIF3C EIF3D EIF3E EIF3F EIF3G EIF3H EIF3I EIF3J EIF3K EIF3L EIF3M EIF4A1 EIF4A2 EIF4B EIF4E EIF4G1 EIF4H EIF5 FAU RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4X RPS4Y1 RPS4Y2 RPS5 RPS6 RPS7 RPS8 RPS9 RPSA