嘌呤分解代谢
中文名称
通路描述
嘌呤碱基鸟嘌呤和次黄嘌呤（由腺嘌呤通过嘌呤 salvage 途径中的事件衍生而来）被转化为黄嘌呤，然后转化为尿酸，尿酸从体内排出（Watts 1974）。该途径在人类和灵长类动物中的终点是不寻常的。大多数其他哺乳动物进一步代谢尿酸以产生更可溶的最终产物，关于高尿酸水平在正常人体生理中可能发挥的潜在作用仍有大量推测。
英文描述
Purine catabolism The purine bases guanine and hypoxanthine (derived from adenine by events in the purine salvage pathways) are converted to xanthine and then to urate uric acid, which is excreted from the body (Watts 1974). The end-point of this pathway in humans and hominoid primates is unusual. Most other mammals metabolize uric acid further to yield more soluble end products, and much speculation has centered on possible roles for high uric acid levels in normal human physiology.
所含基因
10 个基因