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Utilization of Ketone Bodies

Reactome ID: R-HSA-77108

中文名称

酮体利用

通路描述

酮体中丙酮的水平低于乙酰乙酸和β-羟基丁酸的水平。丙酮不能转化为乙酰辅酶A,并通过尿液排出或通过肺部呼出。非肝外组织通过β-羟基丁酸依次转化为乙酰乙酸、乙酰乙酸辅酶A,最终转化为乙酰辅酶A(Sass 2011)。
英文描述
Utilization of Ketone Bodies The levels of acetone in ketone bodies are much lower than those of acetoacetic acid and beta-hydroxybutyric acid. Acetone cannot be converted back to acetyl-CoA, and is excreted in urine, or breathed out through the lungs. Extrahepatic tissues utilize ketone bodies by converting the beta-hydroxybutyrate successively to acetoacetate, acetoacetatyl-CoA, finally to acetyl-CoA (Sass 2011).

所含基因

4 个基因