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Beta oxidation of myristoyl-CoA to lauroyl-CoA

Reactome ID: R-HSA-77285

中文名称

肉豆蔻酰-CoA到棕榈酰-CoA的β氧化

通路描述

β氧化螺旋的第二次通过始于饱和脂肪酸肉豆蔻酰-CoA(来自β氧化螺旋的第一次摆动),并产生棕榈酰-CoA。从LCAD CoA脱氢酶(长链)活性开始,需要四个酶促步骤,然后进行三个酶促步骤,包括烯酰-CoA水合酶、3-羟基酰-CoA脱氢酶和酮酰-CoA硫基酶活性,这些活性均存在于与线粒体膜相关的三功能蛋白中。
英文描述
Beta oxidation of myristoyl-CoA to lauroyl-CoA The second pass through the beta-oxidation spiral starts with the saturated fatty acid myristoyl-CoA (from the first swing through the beta oxidation spiral) and produces lauroyl-CoA. Four enzymatic steps are required starting with LCAD CoA dehydrogenase (Long Chain) activity, followed by three enzymatic steps, enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, and ketoacyl-CoA thiolase activities, all present in the mitochondrial membrane associated trifunctional protein.

所含基因

3 个基因